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Jane Matilda Hadlock Sanford Preble (1826-1898) was the Parisian-born daughter of Capt. Samuel Hadlock Jr. and Hanna Caroline Dorothea Russ.
In 1843, she married George E. Sanford (1812-1873) and bore three children.
Widowed at age 49, she became the second wife of William Pitt Preble of Great Cranberry Island. She lived in the Preble House as an infant and returned as its mistress.
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